Pyrimidin-2-amine
WebSep 20, 2024 · In our previous work, a camphor-based small molecular fluorescent probe pyrimidin-2-amine derivative (CPA) had been developed for the detection of N 2 H 4 … WebMay 18, 2010 · The invention provides a novel method for synthesizing 4-chloropyrrolo[2,3-d]pyrimidine, belonging to the technical field of chemical synthesis. The method comprises the steps of carrying out four-step reaction by using ethyl cyanoacetate, thiourea, caustic alcohol, 2-chloroacetaldehyde and sodium acetate as raw materials and using alcohol, …
Pyrimidin-2-amine
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WebBioaccumulation Estimates from Log Kow (BCFWIN v2.17): Log BCF from regression-based method = 0.456 (BCF = 2.856) log Kow used: 1.50 (estimated) Volatilization from Water: Henry LC: 7.91E-014 atm-m3/mole (estimated by Bond SAR Method) Half-Life from Model River: 1.233E+010 hours (5.136E+008 days) Half-Life from Model Lake : 1.345E+011 … WebA Pyrazolo[3,4-D]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants. / Yoon, Hojong; Kwak, Yeonui; Choi, Seunghye et al. In: Journal of Medicinal Chemistry, Vol. 59, No. 1, 14.01.2016, p. 358-373. Research output: Contribution to journal › Article › peer-review
Webthe physical and chemical property of 152460-10-1, 4-Methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline is provided by ChemNet.com WebDec 15, 2024 · A detailed theoretical study was implemented on a novel drug molecule “Pyrimidin-2-amine (PA)”.Density functional theory (DFT) and time-dependent density …
WebContact Hongkong, China Trader LEAP CHEM CO., LTD. for the product 1H-Pyrazolo[4,3-d]pyrimidin-7-amine, 3-methyl- (9CI). Chat now for more business. WebFeb 13, 2024 · To a solution of pyrimidin-2-amine (1.0 g, 0.010 mol) in DMSO (10 mL) was added iodine (3.2 g, 0.012 mol). The reaction mixture was stirred at 120°C for 1 h. The …
WebSynthesis of pyrimidines. An oxidative annulation involving anilines, aryl ketones, and DMSO as a methine (=CH−) equivalent promoted by K 2 S 2 O 8 provides 4-arylquinolines, …
Web3-(2-Phenoxyphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine is a useful research compound. Its molecular formula is C17H13N5O and its molecular weight is 303.325. The purity is usually 95%. BenchChem offers high-quality 3-(2-Phenoxyphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine suitable for many research applications. e-tax 受信通知 スマホWebJul 12, 2024 · This study aimed to design and synthesize a series of novel pyrimidine derivatives containing an amide moiety, and investigate their in vitro antifungal activities … e-tax 受信通知 ダウンロードWebAstatech 1-(PYRIMIDIN-2-YL)PIPERIDIN-4-AMINE 2HCL; Purity-97%; MDL-MFCD11052947 - AST (Additional S&H or Hazmat Fees May Apply) The store will not … e-tax 受信通知 ダウンロードできないWebMar 25, 2024 · With the desire to discover novel, potent, and selective CDK2 inhibitors, the phenylsulfonamide moiety of our previous lead compound 1 was bioisosterically replaced with pyrazole derivatives, affording a novel series of N,4-di(1H-pyrazol-4-yl)pyrimidin-2-amines that exhibited potent CDK2 inhibitory activity. etax 受信通知 スマホWebJul 3, 2024 · N-(4-(2-(Dimethylamino)ethoxy)-2-methoxy-5-nitrophenyl)-4-(l-methyl-lH- indol-3-yl)pyrimidin-2-amine (Scheme 1, Intermediate B). To a slurry of NaH (30 mmol, 60% … e-tax 受信通知 スマホ 見れないWebMar 9, 2024 · Cyclin D dependent kinases (CDK4 and CDK6) regulate entry into S phase of the cell cycle and are validated targets for anticancer drug discovery. Herein we detail … e-tax 受信通知 メール詳細WebMay 24, 2024 · Herein, we describe the discovery of (E)-4-(3-arylvinyl-1H-indazol-6-yl)pyrimidin-2-amine derivatives as potent PLK4 inhibitors with more concise structure using a scaffold hopping strategy. SAR exploration and preliminary assessment identified 14i as a new PLK4 inhibitor which displayed excellent potency in vitro. e-tax受信通知 どこでもらえる